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Res Synth Methods 3
Always direct the water stream down the vial wall rather than directly onto the powder to minimize foaming and preserve peptide integrity
Prior to the widespread adoption of lipidation, albumin binding, and fusion strategies, many peptides were dismissed as clinically impractical solely because of their dosing frequency
Victoza (liraglutide): A daily injectable option that may work better for those who prefer smaller, more frequent doses
The sample were then vortexed and centrifuged (15,000 g , 5 min, 16 C) to sediment the precipitated protein