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This translates to 40 to 44 pounds for someone starting at 200 pounds, or 60 to 66 pounds for someone starting at 300 pounds

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Trial results vary by drug, dose, baseline weight, adherence, side-effect tolerance, and whether patients can stay on treatment

Thursdays readout could cast an even longer shadow of doubt over Novos obesity pipeline, particularly after the disappointing Phase II results for its small molecule oral cannabinoid receptor 1 agonist monlunabant, which in September showed modest weight reductions muddied by psychiatric side effects

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