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doi:10.1016/S1357-2725(99)00138-7

Semaglutide is meant for long-term use to manage chronic conditions like type 2 diabetes and obesity

But that efficacy comes with the GI side-effect baggage

The growing body of clinical evidence supporting the long-term efficacy and safety of agents such as semaglutide and tirzepatide has strengthened physician confidence and expanded reimbursement coverage in key markets Moreover, the rising interest from younger demographics, increased public awareness through social media, and celebrity endorsements are normalizing the use of obesity drugs, further accelerating consumer demand

Mol Med 30(1):218 Sharma AR, Chatterjee S, Lee YH, Lee SS (2024) Targeting crosstalk of signaling pathways among Muscles-Bone-Adipose tissue: A promising therapeutic approach for sarcopenia

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