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Res., 2003, 21, 976983)

Animal studies showing gut effects used oral doses roughly in the range of 10 mcg per kg body weight

Beginners often start on the lower end (around 100-200 mg) to assess tolerance, then may increase to higher doses (500+ mg) in later sessions

In addition, superoxide anion may also react with nitric oxide (NO) to form peroxynitrite (ONOO - ), a potent ROS [1317]

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