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Label expansions in 2024 created new reimbursement pathways, leading to sharp increases in GLP1 use among Medicare patients, a population historically excluded from weightloss coverage

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However, this inhibitory effect is significantly weakened in patients with T2DM, indicating that its potential application in diabetes treatment requires further investigation

In DAPA-CKD, among 4,304 participants (67.5% with type 2 diabetes mellitus and 15.3% with prediabetes at baseline), the mean eGFR was 43.1 mL/min/1.73 m and the median UACR was 949 mg/g [47,52]