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In animal models degarelix had lower activity for histamine release than the other LH-RH antagonists, ganirelix, abarelix, and cetrorelix 32

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Curcumin dose-dependently reversed PPA-induced deficits in social interaction, repetitive behaviors, anxiety, locomotion, learning and memory, while normalizing oxidative stress, mitochondrial dysfunction and pro-inflammatory signaling, supporting its neuroprotective efficacy in this ASD model (Yang et al., 2020)

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