Acidosis is due to reduced feedback inhibition of -glutamyl cysteine synthetase in the gamma-glutamyl cycle, which ultimately leads to overproduction and accumulation of 5-oxoproline
Tomofuji Y, Kishikawa T, Maeda Y, et al
Research context: For evidence on mechanisms, human and preclinical research, limitations, and safety, read 5-Amino-1MQ Peptide: Benefits, Uses, Side Effects, Dosage, and Research
Patent 4,599,232.Dura Carn is a registered trademark of Sigma-Tau Health Science, Inc
Preclinical Research Summary Preclinical research references describe observations associated with CJC-1295 (no DAC) and Ipamorelin derived from controlled experimental systems designed to evaluate synthetic peptide materials within non-clinical research frameworks
Current treatment includes a low fat, high carbohydrate diet and avoidance of fasting which dramatically improves prognosis allowing long term survival