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In individuals with IBD, proinflammatory cytokines downregulate OCTN2 through the PPAR/RXR pathway, resulting in reduced carnitine uptake by intestinal epithelial cells that leads to the dysfunction of intestinal regeneration and repair and further deterioration of IBD [232]

Our goal is to move the field toward effective, accessible treatments that can slow or even reverse liver damage before patients reach liver failure. Co-authors include Jacob George, Westmead Institute for Medical Research

It is distributed in the body via this before it is finally excreted with the urine

This results in softer, more supple skin with increased resistance to environmental stressors

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Can Fam Physician 2001