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Rather than incremental escalation, clinicians should consider early initiation of dual or triple therapy in patients with persistent albuminuria despite optimized RAAS inhibition

Since the diversity of gut microbiota erodes during aging, dysbiosis could also be a reason for high susceptibility of older adults to severe COVID-19 248

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B12 is safe for most people

Some users report joint discomfort during significant weight loss phases, likely related to the mechanical and structural adaptations required as load-bearing changes