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198,199 p53 in other pathological settings p53 not only plays an important role in the occurrence and development of tumors but is also closely related to many nontumor diseases, such as neurodegenerative diseases (NDDs) and metabolic diseases (Fig

This combination may give more overall results than using either compound alone

Perhaps most critically, these increasingly high-dimensional transcriptomic datasets have empowered a new generation of computational tools that not only model and predict aging trajectories but also simulate interventions capable of reversing them

An exemplary batch of gel formulation as described in Example Al is prepared containing, for example, 1.5% of transplatin is prepared by dissolving Poloxamer 407 (BASF Corp.) in 50 mM Tris buffer and 77 mM NaCl solution with a pH between 5.5-8.0

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