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Alterations in energy metabolism in cardiovascular diseases often involve systemic pathophysiological changes across multiple systems, while the key energy metabolic targets (AMPK, SIRT) exhibit functional variances in different tissues, suggesting the need for in-depth mechanistic exploration using tissue-specific animal models and expanding clinical research in the future

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The brain also contains high concentrations of vitamin C

Kong R, Ji L, Pang Y, Zhao D, Gao J

70,71,72 Moreover, study indicates that combining serum AFP with MTHFD1 enhances the prognostic prediction accuracy in hepatocellular carcinoma (HCC)