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Excessive Vitamin B12 May Increase the Risk of Lung and Colon Cancer A large-scale 2017 study published in the Journal of Clinical Oncology found that males who supplemented with megadoses of vitamins B6 and B12 had a 30% to 40% increased risk of lung cancer compared to individuals who did not supplement

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Statistical analysis was done using a One-Sample t-Test (s0 (fold change) = 0.1, FDR = 0.05)

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