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The study population (30.7% women) was predominantly Caucasian (75.4%) with an average age of 60.3 years, a mean duration of diabetes of 9.3 years, an average A1C of 7.7%, and an average eGFR of 76 mL/min/1.73 m 2

Additionally, a dose-dependent increase in the B-cell lymphoma 2 (BCL-2)/Bcl-2associated X protein (BAX) was observed, indicating a shift toward cell survival

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Key Monitoring Steps for Safe Dual Therapy Before starting semaglutide, inform your primary care provider about your Synthroid dose and ask for baseline TSH, free T4, and free T3 testing