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High blood sugar levels due to poor insulin use (high glucose levels) can damage endothelial cells the cells lining blood vessels, lymphatic vessels, and organs and cause oxidative stress

Cooray, S

Clinical consensus suggests that 2g twice daily of myo-inositol should be used to treat PCOS for metabolic, hormonal and ovulation benefits and to prevent gestational diabetes ( International Consensus Conference on Inositol in Obs & Gyne 2015 )

In both clinical research and wellness settings, dosing is relatively consistent low microgram amounts designed for daily use

For example, Bristol Myers Squibb replaced the naphthalene ring with a trifluoromethyl-containing benzene during the development of BMS-641988 for the treatment of prostate cancer 13

Start low : 250500mcg per day is sufficient for most goals Avoid front-loading unless medically directed Stick to a 26 week cycle unless guided by a professional A bell-shaped dose-response has been observed with BPC-157, meaning excessive dosing may reduce or reverse therapeutic effects. Sikiric, P