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Clinical trial data submitted to the MHRA and EMA document headache as common (affecting 1 in 10 to 1 in 100 people) with diabetes formulations, and very common (more than 1 in 10) with higher weight-management doses

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Relation to the Hill Equation [edit] The EC 50 relates to the Hill equation, which is a function of the agonist concentration, [A]: where E is the observed response or effect above baseline, and n, the Hill coefficient reflects the slope of the curve