IECs may utilize glucose generated from acetyl CoA by the oxidative phosphorylation of pyruvate under typical conditions
To this end, a number of protocols have been developed that employ growth factors and small molecules to activate pathways in a developmentally relevant order 1,3,4,5,6,7,8,9
Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen JE, Wang Z, Wencai M, Lee HC, Orlowski R, Sarbassov DD, Neelapu SS, McDonnell T, Miranda RN, Wang M, Kantarjian H, Konopleva M, Davis, RE, Andreeff M
Boost performance
For instance, Wegovy delays gastric emptying, which may have implications for anaesthesia and requires discussion with the surgical team
Managing diabetic foot ulcers is rarely about the ulcer alone