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Dietary Considerations Focus on a nutrient-dense, balanced diet that emphasizes whole, unprocessed foods

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Tirzepatide stimulates both GLP-1 and GIP receptors, producing 2025% greater weight loss than semaglutide in clinical trials for some patients

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The appetite-suppressing effects of semaglutide allow many patients to achieve a caloric deficit more naturally, while metformin addresses the underlying insulin resistance that often perpetuates weight gain