changing from tirzepatide to retatrutide How Switch To Retatrutide: The Right (& Wrong) Way Retatrutide vs Tirzepatide (2026): Differences

This isn't an arbitrary choice

Some providers and patients interpret this as the medication not working but its usually just the pharmacology

Research has shown that pharmacological inhibition of the AMPK pathway increases cardiomyocyte mortality, suggesting a protective effect on AMPK-associated cardiomyocyte autophagy

For women with PCOS, GLP-1 microdosing protocols may help: Improve insulin sensitivity Support weight management Reduce cravings and appetite swings Enhance metabolic health By using microdoses tailored to each patient, we can minimize side effects while targeting one of the key drivers of PCOS insulin resistance

Norepinephrine is a neurotransmitter that plays a role in regulating appetite, metabolism, and energy expenditure

Plus, part one featured a brief interview with fellow pharmacist podcaster Dr