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These beneficial bacteria are champions for your gut health, which could have a knock-on effect of boosting the secretion of GLP-1 in your body

The goal is maximum consistent therapeutic effect

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Metformin has a known GI effect that tends toward looser stools in some patients, which can partially offset GLP-1-related constipation

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Source: New England Journal of Medicine - STEP 1 Trial 20% lower risk of heart attack and stroke SELECT trial showed semaglutide reduces major cardiovascular events (death, heart attack, stroke) by 20% in people with obesity