This product is intended for Research Use Only (RUO)
But about two months after that announcement, Costco and Sesame noticed that customers were inquiring about weight-loss help and began working on a new program to address that interest, said Sesame co-founder and CEO David Goldhill
Early GLP-1 manufacturers, including Novo Nordisk and Eli Lilly, originally developed the drug to help with blood sugar control in adults with type 2 diabetes, but weight loss has since become the primary driver of adoption, he says
Also, while the indazole intermediate (5a) is commercially available, Lilly elected to prepare it in two additional steps from simpler, less expensive starting materials
No claims are made regarding medical, therapeutic, or clinical outcomes
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