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Abstract In this review, we synthesize recent conceptual and experimental advances in neuroscience, highlighting selected studies that delineate the roles of reactive microglia and astrocytes in the contexts of developmental inflammatory stress, neurodegenerative diseases, and cellular senescence

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Furthermore, the metabolism of PUFAs is related to the formation of toxic byproducts, especially 4-hydroxynonenal (4-HNE), leading to the initiation of ferroptosis (Zhong and Yin, 2015)