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Polycystic ovary syndrome, oral contraceptives and metabolic issues: new perspectives and a unifying hypothesis

Recent phase 3 TRIUMPH4 data (Dec 2025) showed 28.7% loss over 68 weeks, exceeding semaglutide (1517.5%) and tirzepatide (22.5%)

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It is worth noting that we used TAT peptide as the control peptide in this study rather than the second N-terminus fragment of DAT (A 16 P 26 ) from our previous study [23]

Skillbck et al