A., Cutler, G
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The naturally occurring endocannabinoid anandamide also caused similar 24 h loss of cell viability in developing mouse cortical neurons at concentrations ranging from 1 to 100 mcg/mL, indicating the mechanism of cell death could be mediated through the cannabinoid receptors
However, data from a phase II clinical trial involving pasireotide in patients with dumping syndrome, where progressively increasing doses of pasireotide were added with repeated OGTT testing, show that up to 50% of patients continued to display hypoglycaemia during treatment 86
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