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Oral and topical treatment of painful diabetic polyneuropathy: practice guideline update summary: report of the AAN Guideline Subcommittee

AOD9604 has fewer reported side effects and is better tolerated

Microneedling involves the use of fine needles to create minute punctures into the skin, thereby stimulating collagen production

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95% CI, 0.72 to 0.90

These established companies have built defensible competitive advantages through proprietary production technologies, vertically integrated manufacturing facilities, and extensive distribution relationships spanning multiple geographies and customer channels