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"Safe treatment requires ongoing care and monitoring by a trained healthcare professional." Federal regulators share that concern: the FDA has reported adverse events, some requiring hospitalization, tied to dosing errors with unapproved compounded versions

Clinicians should conduct targeted investigations when fatigue persists beyond the initial adjustment period

Patients with features such as rapid progression, significant asymmetry, predominant motor symptoms, severe autonomic dysfunction, or unexplained weight loss should receive expedited evaluation, as these may indicate alternative or additional diagnoses requiring different management approaches