Science 250(4980):559-62, 1990
DOX induces intracellular accumulation of oxidized phospholipids, which upregulates HO-1 expression via Nrf2, leading to cardiac heme degradation and release of free iron
Stopping GLP-1 drugs can quickly erase cardiovascular benefits Even brief interruption tied to change in risk of heart attack, stroke and death Sara Moser and Alaska Adams / WashU Medicine Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S
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