Common signs and symptoms include Skin reactions, including hives and itching and flushed or pale skin Wheezing and breathing trouble Slurred speech Shock Nausea, vomiting or diarrhea Low blood pressure (hypotension) Facial swelling Dizziness or fainting Difficulty swallowing Constriction of airways and a swollen tongue or throat Anxiety and confusion Abdominal pain A weak and rapid pulse There are not many known risk factors for anaphylaxis, but certain things may increase the potential risk associated with the condition and these include previous anaphylaxis, allergies or asthma and certain other conditions (like heart disease and an abnormal accumulation of a certain type of white blood cell (mastocytosis)
For others, the stimulant effect, the dry mouth, or the insomnia tips things in the other direction
Preclinical research demonstrated that NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% , shrank adipocyte size by 30-40%, and lowered plasma cholesterol by ~30% all without affecting food intake
MOTS-C A peptide derived from mitochondrial DNA that improves energy metabolism, insulin sensitivity, and exercise capacity
87 , e0017422 (2023)
Strong preclinical evidence