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You might take berberine with main meals (to reduce gastrointestinal effects and support its glucose-modulating actions) and L-carnitine either with meals or separately, depending on your routine and tolerance

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Older adults (over 60) losing weight on GLP-1 medications face higher risks from muscle loss because age-related sarcopenia is already reducing their lean mass

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It has low biological activity and needs to be converted to a more active form by the liver