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During WIREDs Big Interview event in San Francisco on Thursday, Topol told features editor Sandra Upson that while he was working on Super Agers he learned that theres a difference between lifespan and health span and that neither has much to do with genetics

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They set out to examine the effect of "pineal gland peptide preparation"epithalaminon elderly patients with accelerated aging of the cardiovascular system, and found that long-term treatment with 50-milligram injections of epithalamin every 6 months for a duration of 12 years lead to decreased cardiovascular aging as well as decreased overall functional age

Fat distribution shifts from peripheral to central

And because they can cause muscle loss along with fat loss, pairing medication with strength training and adequate protein is key

Knott et al