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doi: 10.1016/j.archoralbio.2019.05.009 150 LeeNKimW-U

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This is significant because leptin has its primary effects in the brain but does not cross the blood-brain barrier as readily as MT-2

Its a challenge due to patients lack of adherence to long-term medication use, as well as difficulties in identifying poor blood pressure control and modifying therapy accordingly

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The weight of these studies is between 10.1 and 23.4%, and the total number of participants is between 3297 and 9901