Further evidence has increased the understanding of GIP showing that GIP likely still has a role in diabetes despite normal or sometimes elevated concentrations
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1.1 Expanded indications and increasing disease prevalence In addition to type 2 diabetes and weight management as key battlegrounds today, GLP-1 therapies have shown clinical promise in treating a wider array of conditions, including Alzheimers disease, cardiovascular risk reduction , MASH (metabolic dysfunction-associated steatohepatitis) and chronic kidney disease (CKD)
Although there have been mixed results with regard to the amount of incretin secretion, a meta-analysis showed that the secretion of GLP-1 and GIP is not reduced in patients with type 2 diabetes compared to their counterparts without diabetes [18,19]
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If you are having any side effects, that means that the dose is too high