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Classical and novel antiarrhythmic drug paradigms In contrast to the inherited channelopathies, where insights into mechanisms of arrhythmia have greatly advanced antiarrhythmic drug therapy, the ICD remains the cornerstone of antiarrhythmic therapy in patients at high risk for ventricular arrhythmias due to acquired conditions [47]

Researchers found that adults with severe anhedonia, depression, and anxiety who received PAT experienced greater overall clinical improvement than those who underwent a traditional therapy centered on reducing negative symptoms

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