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Even the mere thought of food can divert our attention from other unpleasant things

These metabolic improvements persisted for as long as participants stayed on the medication, which reinforces the case for not stopping

Together, they orchestrate a crucial hormonal regulation known as the incretin effect

Bottom Line GLP-1 medications are reshaping obesity treatment, but they are not magic weight-loss solutions or performance enhancers

Moreover, exendin-4 inhibits NF-B activity by hindering the breakdown of IB (NF-kappa-B inhibitor alpha) in LPS-stimulated primary microglia, which reduces the activation of microglia and the generation of pro-inflammatory cytokines [113]

GLP-1 also activates receptors in the brain and stomach, helping to regulate appetite and digestion