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After berberine treatment, allergic symptoms, IgE levels, and GATA-3 and T-bet expression were decreased, whereas Foxp3 expression and the Treg cell population were increased

Immunomodulatory effect of Bifidobacterium breve on experimental allergic rhinitis in BALB/c mice

However, in preclinical studies, BPC-157 has been examined in animal models involving the gut, muscles, tendons, ligaments, and nervous system

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10.1002/mds.28375 47 NagatsuT.NakashimaA.IchinoseH.KobayashiK

Temporary fatigue or mild flulike symptoms sometimes occur during the first 1-2 weeks as the body adjusts to enhanced detoxification activity