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Tirzepatide has shown similar results: in a phase 2 trial, up to 73.3% of participants at the highest dose achieved MASH resolution without worsening fibrosis at 52 weeks, compared to 13.2% on placebo

Lower Risk of Overdoing It Semaglutide has powerful effects on appetite, and for some people, higher doses may cause more suppression of hunger than they are comfortable with

The Journey Begins: Initial Effects and Early Signs When starting a GLP-1 medication therapy journey, patients can expect to notice initial effects and early signs of the medications impact on their weight and metabolic health within the first few weeks of treatment

While this field is still emerging, progress has been rapid, particularly given the increasing use of artificial intelligence [53]

Gupta, S., Hawker, G