The hormonal shifts of perimenopause and menopause frequently trigger or worsen depression and anxiety, even in women with no prior psychiatric history
Patients with a del15q genotype tend to have higher BMI (137, 176, 177) and HbA1c levels, despite similar values of glycemia, insulinemia, insulin resistance, body composition, metabolic profile, adipocyte size, resting energy expenditure, hyperphagia score, and levels of ghrelin compared to those with mUPD, suggesting a possible association between mUPD genotype and a more adverse metabolic profile, even when adjusted for BMI
March 9, 2026
Consistently doing more work leads to superior adaptations in muscle and strength gains
Important caveat: if your B12 levels are already adequate, supplementation will not boost your energy beyond baseline
GLP-1 is also consistent with the conclusion that GLP-1 can inhibit liver lipid synthesis [51]