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This fungal infection develops when medication residue remains in the mouth and throat after each use

Molecular size directly limits mucosal permeability, and peptides above a certain threshold do not cross the sublingual epithelium in clinically predictable amounts

Crosstalk between oxidative stress and inflammatory nodes is central to this network: PI3K/AKT can promote Nrf2 activation and antioxidant gene expression, while activated Nrf2 dampens NF-Bdriven transcription and limits ROS-mediated injury (Sheikh et al., 2025)

[8] In such patients, MB should be avoided or used only with close monitoring, and at minimum, dosage reduction is advised

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