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Dev Cell (2020) 54:720

Dehydration can worsen common side effects like nausea and fatigue

Abnormal IGF-1 levels can lead to various health problems: Excessively high levels of IGF-1 at any stage in life can cause a rare condition known as acromegaly (gigantism)

Manufacturing and Supply Considerations The complexity of tirzepatide manufacturing has led to supply constraints that limit patient access