Patients on GLP-1s who are not doing any resistance training are losing more muscle than they need to
Practical implementation considerations include: Post-meal activity : Even light walking (10-15 minutes) after meals may improve postprandial glucose levels Reducing sedentary time : Breaking up prolonged sitting with brief activity every 30 minutes Consistency over intensity : Regular moderate activity provides greater metabolic benefit than sporadic vigorous exercise Individualization : Exercise prescriptions should account for baseline fitness, comorbidities, and personal preferences to optimize adherence Special precautions are needed for those with diabetes complications, including proper footwear with neuropathy, avoiding high-impact or head-down exercises with retinopathy, and appropriate cardiovascular assessment before beginning vigorous exercise
This helps prevent overeating and encourages more controlled portions, making it easier for individuals to stick to their weight loss goals
An unhealthy gut microbiome can influence satiety hormones, inflammation, and insulin signaling GLP-1s are a mixed bag of results for your metabolic triad
Lancet Diabetes Endocrinol (2017) 5(5):35566
Background: How GLP-1s evolved from diabetes treatment to anti-obesity medications Glucagon-like peptide-1 receptor agonists (GLP-1s) have a notable history in medical treatment, beginning as therapies for type 2 diabetes and later emerging as highly effective agents for weight loss
