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Eaton, M., Hernandez, L

J Cardiovasc Dev Dis

Moreover, it is increasingly recognized that weight loss itself primarily serves as a surrogate marker for favorable changes in body fat distribution, particularly reductions in ectopic fat depots such as visceral adipose tissue and intrahepatic lipid content, both of which are strongly associated with ASCVD risk (80, 81)

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This suggests that trevogrumab alone, without garetosmab, may offer a more viable safety profile for clinical practice

If you are not seeing results by this point, it is time to evaluate your protocol with your provider