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Handb Exp Pharmacol (2016) 233:43759

Individuals with defective carnitine transport have poor intestinal absorption of dietary L-carnitine, impaired L-carnitine reabsorption by the kidneys (i.e., increased urinary loss of L-carnitine), and defective L-carnitine uptake by muscles (4)

In clinical studies, it is advised to use various evaluations such as symptoms, signs, nerve conduction studies (NCS), quantitative sensory testing (QST), and autonomic tests to assess the severity of diabetic polyneuropathy effectively

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