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doi: 10.1016/j.fertnstert.2017.01.001 5

Telling her to "just take the medication" dismisses the importance of breastfeeding

In AN patients and in rodent AN models, chronic food restriction induces profound alterations in the ghrelin signaling that leads to the development of inappropriate behaviors like hyperactivity or addiction to food starvation and therefore a greater depletion in energy reserves

The practical effect of longer duration is that trials can measure outcomes over weekly and multi week windows with consistent exposure, rather than focusing only on short time course endpoints

When insulin requirements drop by 2030%, CGM data becomes even more critical

These concepts reflect a more deliberate, data-driven approach to eating