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In conclusion, our findings indicate that metformin may alleviate OA pain and partially attenuate the pathological changes associated with OA, suggesting a potential protective role

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Potential cardiovascular and renal concerns have emerged from observational research

No obvious systemic adverse reactions were observed in tested animals even at a relatively high daily dose up to 60 mg/kg/d, confirming its promising safety profile and therapeutic efficacy for prospective ovarian cancer treatment

(TNF-), interleukin (IL)-1, IL-6, IL-8, IL-10, IL-12, and interferon- (IFN) are produced by thyroid follicular cells and intra-thyroidal inflammatory cells

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