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Yet, while their ability to reduce body weight and insulin levels was greater than GLP1 monotherapy in male models 33,34,35 , the potential of these GLP1-based multi-agonists for the treatment of the metabolic, hormonal, and gonadal complications associated with PCOS has not been explored to date

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Research examines convergent Gs / cAMP / PKA signalling across the three incretin receptors and downstream effects on energy expenditure pathways in animal models

These elevations resolved without intervention in most cases

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