Metformin, commonly prescribed for diabetes, and proton pump inhibitors used for acid reflux can both reduce B12 absorption over time
It inhibits NNMT (nicotinamide N-methyltransferase), an enzyme regulating metabolism, fat storage, and NAD+ consumption.[4][27][6] NNMT methylates nicotinamide, a NAD+ breakdown product, diverting it from recycling and reducing available NAD+
As with any treatment, its important to discuss any concerns with your healthcare provider before starting a weight loss or wellness regimen to ensure its the right choice for your health
(PubMed) Bressa GM
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B-12 Supports Weight Loss and Boosts Your Metabolism New research finds a link between B-12 deficiency and obesity among American adults