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Inhibition of Gastric Inhibitory Polypeptide Signaling Prevents Obesity

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Adem A, Ekblom J, Gillberg PG, Jossan SS, Hg A, Winblad B, Aquilonius SM, Wang LH, Sara V (1994) Insulin-like growth factor-1 receptors in human spinal cord: changes in amyotrophic lateral sclerosis

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Without resistance training, that deficit leads to indiscriminate weight loss that includes significant muscle mass

Therefore, by treating insulin resistance with Metformin, people may be able to reduce their risk of developing cognitive problems later in life