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When stimulated, PLC may catalyze the production of two major second messengers: IP3 and diacylglycerol (DAG)

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For poor circulation, 2 x 500mg servings per day is enough, whereas for blood vessel disorders, or for people looking to increase athletic performance, 1000mg 1500mg twice per day (2000mg 3000mg in total) is recommended

It's worth noting that some long-acting GLP-1 agonists (such as semaglutide at higher doses) can still cause significant nausea despite their extended half-life

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