In Alzheimers disease, six-month treatment with GLP-1 analogue prevents decline of brain glucose metabolism: randomized, placebo-controlled, double-blind clinical trial
They form complexes and reduce the mobility of Arsenic in the root regions
It was FDA-approved for chronic weight management in November 2023 under the brand name Zepbound, and it's also approved for type 2 diabetes under the brand name Mounjaro
[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Vaccaro O, Masulli M, Nicolucci A, Bonora E, Del Prato S, Maggioni AP, Rivellese AA, Squatrito S, Giorda CB, Sesti G, Mocarelli P, Lucisano G, Sacco M, Signorini S, Cappellini F, Perriello G, Babini AC, Lapolla A, Gregori G, Giordano C, Corsi L, Buzzetti R, Clemente G, Di Cianni G, Iannarelli R, Cordera R, Lamacchia O, Zamboni C, Scaranna C, Boemi M, Iovine C, Lauro D, Leotta S, DallAglio E, Cannarsa E, Tonutti L, Pugliese G, Bossi AC, Anichini R, Dotta F, Di Benedetto A, Citro G, Antenucci D, Ricci L, Giorgino F, Santini C, Gnasso A, De Cosmo S, Zavaroni D, Vedovato M, Consoli A, Calabrese M, di Bartolo P, Fornengo P, Riccardi G, Thiazolidinediones Or Sulfonylureas Cardiovascular Accidents Intervention Trial (TOSCA.IT) study group

10.1016/j.jocn.2021.11.029 [DOI] [PubMed] [Google Scholar] 50.Ruan Z, Yang L, Shi H et al (2021) The cost-effectiveness of once-weekly semaglutide compared with other GLP-1 receptor agonists in type 2 diabetes: a systematic literature review
The lawsuit, filed in federal district court in New Jersey, alleges Lilly intentionally selected outdated studies to show the use of Mounjaro and Zepbound lead to significantly more weight loss than Novo Nordisks Ozempic and Wegovy