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It's got to follow state rules for compounding and prescribing

Other things like alcohol

The Basic Properties of B12 and Uses in Health Vitamin B12, also known as cobalamin, is a water-soluble vitamin essential for nerve function, red blood cell production, and DNA synthesis

This class of drugs works by lowering blood sugar levels in multiple ways, without stimulating the pancreas to make extra insulin

A responsible comparison should separate chemical stability from systemic bioavailability, distinguish drug uses from supplement positioning, avoid disease claims and evaluate molecular form, assay, impurities, dosage-form performance and current market-specific regulations