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In the seasonal (community outbreak) prophylaxis trial in elderly residents of skilled nursing homes, about 80%, 43%, and 14% of the subjects were vaccinated, had cardiac disorders, and had chronic airway obstructive disorders, respectively
Weeks 4 to 12: Reduced shedding is often the first sign of response
However, unintended weight loss in patients who are already at a healthy weight can be a concern and should be monitored
Receptor interactions for the remaining residues within the N-terminal 11 amino acids of exendin-4 were similar to those formed by GLP-1, albeit overall interactions deeper within TM2, TM3, TM5, and ECL2 were generally less persistent, and those in TM1 and TM7 were more persistent (Figure 6, Supplemental Table 3, Supplemental Movie 1)
Depressive behavior was measured in terms of lack of escape-oriented behavior, immobility, and plotted as a percentage of the total 6-min time period
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